Bioconductor 3.23 Release!

immLynx

This is the development version of immLynx; for the stable release version, see immLynx.

Linking Advanced TCR Python Pipelines and Hugging Face Models in R


Bioconductor version: Development (3.24)

A comprehensive toolkit that bridges popular Python-based immune repertoire analysis tools and Hugging Face protein language models into the R environment. Provides unified interfaces for TCR distance calculations (tcrdist3), sequence generation probability (OLGA), selection inference (soNNia), clustering (clusTCR), protein embeddings (ESM-2), metaclone discovery (metaclonotypist). Fully compatible with the scRepertoire and immApex ecosystem for single-cell immune repertoire analysis.

Author: Nick Borcherding [aut, cre] ORCID iD ORCID: 0000-0003-1427-6342

Maintainer: Nick Borcherding <ncborch at gmail.com>

Citation (from within R, enter citation("immLynx")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("immLynx")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF

Details

biocViews Annotation, Classification, Clustering, DimensionReduction, ImmunoOncology, MotifAnnotation, Sequencing, SingleCell, Software
Version 1.1.0
In Bioconductor since BioC 3.23 (R-4.6) (< 6 months)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports basilisk(>= 1.8.0), reticulate (>= 1.24), immApex, methods, S4Vectors, SingleCellExperiment, stats, SummarizedExperiment, utils
System Requirements
URL https://github.com/BorchLab/immLynx/
Bug Reports https://github.com/BorchLab/immLynx/issues
See More
Suggests BiocStyle, ggplot2, knitr, markdown, rmarkdown, scater, scran, scRepertoire, spelling, testthat (>= 3.0.0), withr
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64)
macOS Binary (big-sur-arm64)
macOS Binary (sonoma-arm64)
Source Repository git clone https://git.bioconductor.org/packages/immLynx
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/immLynx
Package Short Url https://bioconductor.org/packages/immLynx/
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