Package: iNETgrate
Type: Package
Title: Integrates DNA methylation data with gene expression in a single
        gene network
Version: 1.10.0
Date: 2023-03-24
Authors@R: c(
    person("Ghazal", "Ebrahimi", role = "aut"),
    person("Isha", "Mehta", role = "aut",
    comment = c(ORCID = "0000-0002-6009-0787")),
    person("Hanie", "Samimi", role = "aut"),
    person("Habil", "Zare", email = "zare@u.washington.edu",
    role = c("aut", "cre"), comment = c(ORCID = "0000-0001-5902-6238")))
biocViews: GeneExpression, RNASeq, DNAMethylation, NetworkInference,
        Network, GraphAndNetwork, BiomedicalInformatics,
        SystemsBiology, Transcriptomics, Classification, Clustering,
        DimensionReduction, PrincipalComponent, mRNAMicroarray,
        Normalization, GenePrediction, KEGG, Survival
Depends: R (>= 4.3.0), BiocStyle (>= 2.18.1)
Description: The iNETgrate package provides functions to build a
        correlation network in which nodes are genes. DNA methylation
        and gene expression data are integrated to define the
        connections between genes. This network is used to identify
        modules (clusters) of genes. The biological information in each
        of the resulting modules is represented by an eigengene. These
        biological signatures can be used as features e.g., for
        classification of patients into risk categories. The resulting
        biological signatures are very robust and give a holistic view
        of the underlying molecular changes.
Imports: SummarizedExperiment, GenomicRanges (>= 1.24.1), stats, WGCNA,
        grDevices, graphics, survival, igraph, Pigengene (>= 1.19.26),
        Homo.sapiens, glmnet, caret, gplots, minfi, matrixStats, Rfast,
        tidyr, tidyselect, utils
Suggests: knitr, org.Hs.eg.db, org.Mm.eg.db,
        IlluminaHumanMethylation450kanno.ilmn12.hg19, AnnotationDbi,
        sesameData, TCGAbiolinks (>= 2.29.4)
License: GPL-3
BugReports: https://github.com/Bioconductor/BiocManager/issues
VignetteBuilder: knitr
NeedsCompilation: no
Packaged: 2026-04-29 11:37:32 UTC; root
Author: Isha Mehta [aut] (<https://orcid.org/0000-0002-6009-0787>),
        Ghazal Ebrahimi [aut], Hanie Samimi [aut], Habil Zare [aut,
        cre] (<https://orcid.org/0000-0001-5902-6238>)
Maintainer: Habil Zare <zare@u.washington.edu>
Repository: https://bioc-release.r-universe.dev
Date/Publication: 2026-04-28 13:01:02 UTC
RemoteUrl: https://github.com/bioc/iNETgrate
RemoteRef: RELEASE_3_23
RemoteSha: 27d5942df5b6f4d26c7d3793d7e2702baef6350f
Built: R 4.6.0; ; 2026-04-29 11:45:51 UTC; windows
