Bioconductor release scheduled for October 29

CSOA

This is the development version of CSOA; to use it, please install the devel version of Bioconductor.

Calculate per-cell gene signature scores using cell set overlaps


Bioconductor version: Development (3.22)

Cell Set Overlap Analysis (CSOA) is a tool for calculating per-cell gene signature scores in a scRNA-seq dataset. CSOA constructs a set for each gene in the signature, consisting of the cells that highly express the gene. Next, all overlaps of pairs of cell sets are computed, ranked, filtered and scored.The CSOA per-cell score is calculated by summing up all products of the overlap scores and the min-max-normalized expression of the two involved genes. CSOA can run on a Seurat object, a SingleCellExperiment object, a matrix and a dgCMatrix.

Author: Andrei-Florian Stoica [aut, cre] ORCID iD ORCID: 0000-0002-5253-0826

Maintainer: Andrei-Florian Stoica <andreistoica at foxmail.com>

Citation (from within R, enter citation("CSOA")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("CSOA")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF

Details

biocViews GeneExpression, GeneSetEnrichment, SingleCell, Software
Version 0.99.1
In Bioconductor since BioC 3.22 (R-4.5)
License MIT + file LICENSE
Depends
Imports bayesbio, dplyr, ggeasy, ggforce, ggnewscale, ggplot2, ggraph, ggrepel, graphics, grDevices, kerntools, methods, qs, reshape2, Seurat, SeuratObject, SingleCellExperiment, SummarizedExperiment, sgof, spatstat.utils, stats, textshape, tidygraph, viridis, wesanderson
System Requirements
URL https://github.com/andrei-stoica26/CSOA
Bug Reports https://github.com/andrei-stoica26/CSOA/issues
See More
Suggests BiocStyle, knitr, patchwork, rmarkdown, scRNAseq, scuttle, stringr, testthat (>= 3.0.0)
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64)
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/CSOA
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/CSOA
Package Short Url https://bioconductor.org/packages/CSOA/
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