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### Running command:
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###   /Library/Frameworks/R.framework/Resources/bin/R CMD build --keep-empty-dirs --no-resave-data VariantAnnotation
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* checking for file ‘VariantAnnotation/DESCRIPTION’ ... OK
* preparing ‘VariantAnnotation’:
* checking DESCRIPTION meta-information ... OK
* cleaning src
* installing the package (it is needed to build vignettes)
* creating vignettes ... ERROR
--- re-building ‘VariantAnnotation.Rmd’ using rmarkdown
2025-12-08 18:02:39.635 R[47884:319123184] XType: Using static font registry.
[W::bcf_hdr_check_sanity] GL should be declared as Number=G
--- finished re-building ‘VariantAnnotation.Rmd’

--- re-building ‘ensemblVEP.Rmd’ using rmarkdown

Quitting from ensemblVEP.Rmd:53-58 [lksnv]
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
<error/rlang_error>
Error in `post_Hs_region()`:
! Service Unavailable (HTTP 503).
---
Backtrace:
    ▆
 1. └─VariantAnnotation::vep_by_region(...)
 2.   └─VariantAnnotation::post_Hs_region(...)
 3.     └─httr::stop_for_status(ans)
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Error: processing vignette 'ensemblVEP.Rmd' failed with diagnostics:
Service Unavailable (HTTP 503).
--- failed re-building ‘ensemblVEP.Rmd’

--- re-building ‘filterVcf.Rmd’ using rmarkdown
--- finished re-building ‘filterVcf.Rmd’

SUMMARY: processing the following file failed:
  ‘ensemblVEP.Rmd’

Error: Vignette re-building failed.
Execution halted