On-Target and Off-Target Scoring Algorithms for CRISPR gRNAs

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Documentation for package ‘crisprScore’ version 1.15.2

• DESCRIPTION file.
• User guides, package vignettes and other documentation.
• Package NEWS.

Help Pages

getCasRxRFScores	Calculate on-target sgRNA activity scores for CasRx using CasRx-RF
getCFDScores	Calculate CFD off-target specificity scores
getCRISPRaterScores	Calculate on-target sgRNA activity scores for Cas9 using CRISPRater
getCRISPRscanScores	Calculate on-target sgRNA activity scores for Cas9 using CRISPRscan
getDeepHFScores	Calculate on-target sgRNA activity scores for Cas9 using DeepHF
getEnPAMGBScores	Calculate on-target sgRNA activity scores for enCas12a using enPAM+GB
getLindelScores	Predict frameshift ratios from CRISPR/Cas9 indel prediction using Lindel
getMITScores	Calculate MIT off-target specificity scores for CRISPR/Cas9
getRuleSet1Scores	Calculate on-target sgRNA activity scores for Cas9 using Rule Set 1
getRuleSet3Scores	Calculate on-target sgRNA activity scores for SpCas9 using Rule Set 3
scoringMethodsInfo	data.frame detailing available scoring methods